Page 24 - ISCC'22
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                    October 11-13,   ON CONTAMINATION CONTROL AND
           Antalya TURKIYE  |  2022  CLEANROOM TECHNOLOGY

                                The solution proposed by the works aforementioned are good examples and efforts of ap-
                                plied ventilation concept for Covid-19 prevention purpose, and not for contamination control
                                of products as normally it should be in clean and controlled environments.

                                Generally, for clean environment, it is meant an indoor and confined space where contamina-
                                tion, thermos-hygrometric conditions, air velocity and pressure are controlled within specific
                                values. ISO 14644 (ISO 14644-1, 2015) rules the world or contamination control in cleanroom
                                together with the GMPs GL issued by EMA (EU-GMP- Annex 1, 2008) and FDA (US Food
                                and Drug Administration, 2004) when dealing with sterile drugs and veterinary products.
                                Moreover, sectors where a strict control of contamination is required are broader and span
                                from food&beverage, aerospace, HC applications to semiconductor, etc. The stricter are the
                                requisites of contamination, the more difficult is to handle and to move personnel or semifin-
                                ished products even within the same level of a clean environment without having problems
                                of contamination. The contamination level acceptable in a cleanroom environment is many
                                orders of magnitude less than the one accepted by a civil elevator, in terms of particle size
                                and concentration. Therefore, it comes easy to understand that the way of concepting and
                                designing an elevator for cleanroom is unique because unique is the process and the URS
                                required by the production environment where it is located.
                                Nowadays requests and challenges in cleantech sector require a more flexible and agile
                                production with interconnection of different clean environments for production and han-
                                dling. Moreover, there is lack of indoor space and of green fields for expansion of facility
                                sites usually located in conurbated areas. Therefore, the usage of vertical productions with
                                interconnection through clean lifts will be mandatory in the near future for better space
          TION THROUGH
                                exploitation. In addition to technical problems, a new consciousness in energy saving and
            CONTROLLED          green environment has raised in the last years due to energy cost and climatic changes. The
        ENVIRONMENTS:           new mantra seems to be: “less is better”, where less stands for less energy consumption
            A CLEAN LIFT        and less usage of – plastic – time – manpower for packaging and handling of semi-finished
                                products in dirty or CNC areas back&forth from clean fab areas.
          MULTIPURPOSE          Based on these assumptions, the work here presented deals with the design, building and
                      USE       validation process of a clean lift system dedicated for vertical transportation of personnel and
                                clean products between two cleanroom production  facilities located at different floors. The
                                peculiarities of this study is the presence of difference HVAC and control systems for each
                                cleanroom factories level involved in the studies which makes the project challenging. The
                                solution proposed in this work is based on a class ISO 7 clean lift served by an independent
                                and adaptive HVAC systems with a dedicated control  and environmental monitoring system
                                able to guarantee the desired working and contamination conditions in both cleanroom
                                floors and vertical passages for the quality of products and personnel safety disregarding
                                the outside boundary conditions of the systems and factories.
                                To our knowledge, this is one of the first case studies where a multipurpose clean lift is
                                used in a real clean production process. The main aim of this work is that of introducing a
                                lean manufacturing concept also for a vertical transportation system which must be able
                                to guarantee cleanliness level, safety and productivity by means of the pragmatic design
                                approach and technical solutions adopted in this work.

                                2 CASE STUDY & METHODOLOGY
                                2.1 Case study
                                The solution of the multipurpose clean lift has been conceived for a real application in a
                                biotech company which has two cleanroom production lines, not connected among them,
                                placed at different floors within the same building with classified environments of ISO Class
                                8 according to ISO14644-1 (ISO 14644-1, 2015). Semi-finished products and personnel need
                                to move between the different cleanrooms at different floors. Vertical connection between
                                the two cleanroom production fabs are stairs for personnel and a civil lifts for products. Both
                                vertical connections are not classified and dirty, therefore especially for semi-finished prod-
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