Page 19 - ISCC'22

October 11-13,
50 YOUNG PROFESSIONAL
2022 Antalya TURKIYE | 2022
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of cleanroom and cleanliness technology ensures sterile, microbiologically contamina-
tion-free supply air, circulating air and exhaust air. The degree of permeability of the
textile used can vary and it can be designed as a flexible, elastic or rigid layer. Materials
that can be decontaminated and sterilised in regular operation by UV light of wavelength
222 nm were selected specifically for their use in controlling virus-based contamination.
f After cleaning and sterilisation, the Quarantine -CAPE is designed for multiple use.
f Intelligent, mechanical interfaces allow individual Quarantine units to be linked to
form larger overall systems (see figure 7, right side), so that complete sports halls
can be converted to virus-controlled single-person containment within short times.
f The pandemic-specific, cleanliness-controlled quarantine systems have very low
operating costs due to small-volume multilayer systems.
3.4 Hygienic-CAPE – designed to meet specific pharmaceutical
industry requirements
For the use of temporary, locally limited production capacities for pharmaceutical prod-
ucts, GMP standards must be met above all, in addition to the cross-industry cleanliness
specifications already listed. For this purpose, the surfaces must be designed in such
a way that no reproducible microorganisms, viruses, bacteria, germs or fungi can settle
on the surfaces. At the same time, the materials used must not be metabolisable. This
circumstance is countered by the use of foil-like materials instead of the frequently used
textiles. These are easy to clean, can be disinfected, are highly resistant to chemicals,
have low outgassing behaviour and dissipate electrostatic charges in a defined manner.
CAPE –
The supporting structure of the Hygienic-CAPE is made of a stable, corrosion-resistant
stainless steel frame. This surrounds the CAPE protective cover so that no undercuts FLEXIBLE,
or poorly cleanable composts are installed in the interior area used for the production PORTABLE,
and handling of pharmaceutical products. All construction elements and connecting CLEANROOM
components are hygienically designed.
SYSTEM
Air conditioning is carried out using HEPA filters in combination with irradiation units
to reduce biocontamination. Humidity-controlled air conditioning systems must usually
be used to keep powdery substances free of unwanted agglomeration, e.g. in tablet
production. Air locks with dedicated pressure cascades are used to ensure the absence
of contamination in the internal production area of the CAPE.

3.5 DryClean-CAPE – to achieve very dry and at the same time
very clean environments
For individual, specific applications, such as battery cell production, not only highly
clean but also very dry manufacturing environments are required. Along with the rapid
development in the production of battery-powered vehicles, research and development
environments and initial prototype production areas are needed at very short notice. The
short-term demand for humidity- and cleanliness-controlled fixed installations cannot be
met, also due to interrupted supply chains, so that mobile production environments that
can be installed at short notice have to be used. With the CAPE emodiments described
above, the dryness requirements cannot be met due to the high water permeability of
the textiles used. Instead, a double-shell version of a DryClean CAPE has already been
successfully used by a battery manufacturer for prototype production. This dry clean-
room system, which is equipped with separate material and personnel locks, meets a
dew point of -40 °C (0.08 g/kg abs. humidity) and an air cleanliness class 5 according to
ISO 14644-1 for a production area of approx. 150 square metres. In order to reduce the
special challenges of electrostatic charging of surfaces in extremely dry environments,
the use of an ESD floor in the DryClean environment is indispensable.

4. REALISED CLEANLINESS SPECIFICS OF THE MOBILE CLEANROOM SYSTEM
CAPE data in general
f Wide range of cleanliness classes (Class 1 to 9) according to ISO 14644-1
f Assembly time from 30 minutes up to 3 days
f Clean air supply via filter fan units (FFU) for positive pressure (up to 50 Pa), negative
pressure (up to 30 Pa) or recirculated air